Arhytmogenic Right Ventricular Displasia and Sudden Young Adult Deaths
Abstract
Forensic Medicine specialists often has to deal with sudden-unexpected deaths. Arhytmogenic Right Ventricular Displasia (ARVD) had been defined in 1961, yet previously took place in the textbooks. It is claimed that, this antity is responsible from the sudden deaths of the young adults and athletes. Some of the authors assert that it can be defined not only clinically but also morphologically. Our two different serials revealed that, the criterias which are defined as patognomonic morphology, should be crossed over again in large serials, since these findings are common in randomly selected violent deaths also. In this paper, the findings of the two previous studies are summarized and the proposed morphological criterias of ARVD are criticized.
Key words: ARVD, Autopsy, Medico-legal, Sudden Death, Cardiac Pathology, Right Ventricle.
Downloads
References
2. Gök Ş. ed. Adli Tip 4th ed. İstanbul: Filiz Kitapevi, 1980:52-96.
3. Raymond J R, van den Berg E K, Knapp M J. Nontraumatic prehospital sudden death in young adults. Arch Intern Med 1988;148:303-308.
4. Corrado D, Thiene G, Nava A, Rossi L, Pennelli N. Sudden death in young competitive athletes: Clinicopathologic correlations in 22 Cases. Am J Med 1990;89:588-596.
5. Volta D S. Arrhythmogenic cardiomyopathy of the right ventricle: Thoughts on aetiology. European Heart Journal 1989;10:(Supplement D) 2-6.
6. Thiene G, Nava A, Corrado D, Rossi L, Pennelli N. Right ventricular cardiomyopathy and sudden death in young people. The New England J Med 1988;318(3): 129-133.
7. Marcus FI, Fontaine GH, Guiraudon G, Frank R, Laurenceau JL, Malergue C, Grosgogeat Y. Right ventricular dysplasia: A report of 24 adult cases. Circulation 1982;65(2):384-398.
8. Zipes D P. Specific arrhythmias: Diagnosis and treatment. In Eugene Braunwald ed. Heart Disease A Textbook of Cardiovascular Medicine. 4rth ed. Philadelphia, London, Toronto, Montreal, Sydney, Tokyo: W.B. Saunders Company, 1993:706-707.
9. Zipes D P. Management of cardiac arrhythmias: Pharmacological, electrical and surgical techniques. In Eugene Braunwald ed. Heart Disease A Textbook of Cardiovascular Medicine. 4rth ed. Philadelphia, London, Toronto, Montreal, Sydney, Tokyo: W.B. Saunders Company, 1993:659-661.
10. Zipes D P. Specific arrhythmias: Diagnosis and treatment. In Eugene Braunwald ed. Heart Disease A Textbook of Cardiovascular Medicine. 4rth ed. Philadelphia, London, Toronto, Montreal, Sydney, Tokyo: W.B. Saunders Company, 1993: 697.
11. Smith W M. Mechanisms of cardiac arrhythmias and conduction disturbances. In J.Willis Hurst, Robert A. Schlant, Charles E.Rackley, Edmund H.Sonnenblick, Nanette Kass Wenger eds. The Heart Arteries and Veins. 7th ed. New York, St. Louis, San Francisco, Colorado Springs, Oklahoma City, Auckland, Bogota, Guatemala, Hamburg, Lisbon, London, Madrid, Mexico, Montreal, New Delhi, Paris, San Juan, Sao Paulo, Singapore, Sydney, Tokyo, Toronto: McGraw- Hill Company, 1992: 484.
12. Miller J M, Josephson M E. Ventricular arrhythmias. In William W.Parmley, Kanu Chatterjee, Melvin B. Cheitlin, Joel S.Karliner, Elliot Rapaport, Melvin M.Scheinman eds. Cardiology Physiology, Pharmacology, Diagnosis. 1st ed. Philadelphia, Grand Rapids, London, New York, St.Louis, San Francisco, Sydney, Tokyo: J.B.Lippincott Company, 1992: 4.
13. Caruso G, Frassanito F, Serio G, Pennella A. Is adipose tissue a normal component of the myocardium? European Heart Journal 1989; 10 (Supplement D): 89-91.
14. Bonacina E, Recalati F, Mangiavacchi M, Gronda E. Interstitial myocardial lipomatosis: a morphological study on endomyocardial biopsies and diseased hearts surgically removed for heart transplantation. European Heart Journal 1989; 10(Supplement D): 100-102.
15. Virmani MR, Robinowitz M, Clark CMA, McAllister CHA. Sudden death and partial absence of the right ventricular myocardium. Arch Pathol Lab Med 1982; 106: 163-167.
16. Strain JE, Grose RM, Factor SM, Fisher JD. Results of endomyocardial biopsy in patients with spontaneous ventricular tachycardia but without apparent structural heart disease. Circulation 1983; 68(6):1171-81.
17. Manyari DE, Klein GJ, Gulamhusein S, Boughner D, Guiraudon GM, Wyse G, Mitchell LB, Kostuk WJ. Arrhythmogenic right ventricular dysplasia: A generalized cardiomyopathy? Circulation 1983;68(2): 251-257.
18. Lie JT. Diagnostic histology of myocardial disease in endomyocardial biopsies and at autopsy. In Rosen PP, Fechner RE. eds. Pathology Annual, 1989;2: 254-293.
19. Lobo FV, Heggtveit HA, Butany J, Silver MD, Edwards JE. Right ventricular dysplasia: Morphological findings in 13 cases. Can J Cardiol 1992;8(3): 261-268.
20. Goodin JC, Farb A, Smialek JE, Field F, Virmani R. Right ventricular dysplasia associated with sudden death in young adults. Modern Pathol 1991 ;4(6): 702- 706.
21. Frustaci A. Right ventricular dysplasia vs. idiopathic dilated cardiomyopathy. European Heart Journal 1989;10(Supplement D): 92-94.
22. Pinamonti B, Sinagra G, Salvi A, Lenarda AD, Morgera T, Silvestri F, Bussani R, Camerini F. Left ventricular involvement in right ventricular dysplasia. Am Heart J 1992;123(3): 711-724.
23. Shoji T, Kaneko M, Onedero K, Konnno A, Hasegawa T, Ikeda T, Minase T, Uchiyama S, Iwamoto M. Arrhythmogenic right ventricular dysplasia with massive involvement of the left ventricle. Can J Cardiol 1991 ;7(7): 303-307.
24. Salaçin S, Tuncer İ, Birand A. The intersitisial adipose tissue component of right ventricular myocardium: A histological study on forensic autopsy materials. 4th.Annual Meeting of Mediterranean Association of Cardiology and Cardiac Surgery, 23-27 Sept.1990, Antalya,Turkey. IL Coure 1990;7 (Supplemento).- 235.
25. Salaçin S, Gülmen MK, Çekin N. A Morphological study on the fatty infiltration grades of right ventricle in non-cardiac cases. In Advances in Forensic Sciences, Jacob B, Bonte W. eds. Berlin: Verlag Dr.Köster, 1995:1: 29-34.
26. Mehta D, Odawara H, Ward DE, McKenna WJ, Davies MJ, Camm AJ. Echocardiographic and histologic evaluation of the right ventricle in ventricular tachycardias of left bundle branch block morphology without overt cardiac abnormality. Am J Cardiol 1989;63: 939-944.
The Bulletin of Legal Medicine is an open access scientific journal. Open access means that all content is freely available without charge to the user or his/her institution on the principle that making research freely available to the public supports a greater global exchange of knowledge. The Journal and content of this website is licensed under the terms of the Creative Commons Attribution (CC BY) License. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
The Creative Commons Attribution License (CC BY) allows users to copy, distribute and transmit an article, adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed.
The Bulletin of Legal Medicine requires the author as the rights holder to sign and submit the journal's agreement form prior to acceptance. The authors retain copyright of their work and grant the Association for its publication. This ensures both that The Journal has the right to publish the article and that the author has confirmed various things including that it is their original work and that it is based on valid research.
Authors who publish with this journal agree to the following terms:
*Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
*Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
*Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
