Adli Bilimlerde Aptamer Uygulamaları: Kokain Algılama ve Parmak İzi Belirleme Örneği
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Anahtar Kelimeler

aptamerler
adli bilim uygulamaları
biyosensörler
kokain tayini
gizli parmak izi

Nasıl Atıf Yapmalı

1.
Çağlayan MO. Adli Bilimlerde Aptamer Uygulamaları: Kokain Algılama ve Parmak İzi Belirleme Örneği. Bull Leg Med [Internet]. 05 Nisan 2018 [a.yer 17 Temmuz 2019];23(1):53-9. Erişim adresi: https://www.adlitipbulteni.com/index.php/atb/article/view/1116

Öz

Yapay antikorlar olarak da bilinen aptamerler, farklı boyutlardaki hedef moleküllere, yüksek ilgi ve seçicilik ile bağlanan ve geçtiğimiz 30 yıl içerisinde çok farklı sensör uygulamalarında başarıyla kullanılan yakalama elemanlarıdır. Aptamerlerin bir organizmada üretilen antikorlar yerine laboratuvar ortamında üretilebilmesi, çoğaltılma ve saflaştırma aşamasının kolay olması ve sonsuz konfigürasyonda üretilebiliyor olması gibi eşsiz avantajları vardır. Askeri, çevresel, gıda güvenliği ve tıbbi uygulamalarının yanı sıra, adli bilimlerde de aptamerlerin kullanılması kaçınılmazdır. Bu makalede, aptamerlerin adli bilimlerde uygulamalarına yönelik örnekler verilmiştir. Literatürde, çok sayıda uygulama olması nedeniyle bu makalede, adli bilim ve adli tıpta sensörler için kokain ve adli bilim için parmak izi belirlemesi uygulamaları örnek olarak verilmiştir.

https://doi.org/10.17986/blm.2018136899
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Kaynaklar

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