Aluminium Phosphide Poisoning which Occuring with an Unusual Accident and Resulting in Death: Case Report

Authors

  • Hülya Karadeniz Karadeniz Teknik Üniversitesi Adli Bilimler Enstitüsü, Trabzon , Karadeniz Teknik Üniversitesi Adli Bilimler Enstitüsü, Trabzon
  • Halil Boz Adli Tıp Kurumu, Trabzon Adli Tıp Grup Başkanlığı, Trabzon , Adli Tıp Kurumu, Trabzon Adli Tıp Grup Başkanlığı, Trabzon
  • Hüseyin Çetin Ketenci Adli Tıp Kurumu, Trabzon Adli Tıp Grup Başkanlığı, Trabzon , Adli Tıp Kurumu, Trabzon Adli Tıp Grup Başkanlığı, Trabzon

DOI:

https://doi.org/10.17986/blm.2018238627

Keywords:

Aluminum phosphide, poisoning, autopsy, toxicology

Abstract

Aluminium phosphide is an insecticide that shows highly toxic activity when it reacts with water or moister and becomes phosphine. Because it has high diffusion capacity, it can kill all the organisms in different growth phases in the area that it is used. However, it is used frequently due to not to find rests on plants. There is not a specific antidote for aluminium phosphide and mortality from 30% to 100% in poisoning and it is related with exposure. In this study, we present 13 years girl case who was poisoned by aluminium phosphide. He was found in his apartment which is at first floor, after fumigation of food store at the basement. We aim to evaluate by autopsy findings, chemical and histopathological findings together and to discuss with literature results. In addition, we want to discuss about solution of uncontrolled dealing and using of aluminium phosphide in our country.

Downloads

Download data is not yet available.

References

German JR, Rössel PR. Poisoning with aluminum phosphide can be life-threatening for patients as well as health professionals. Ugeskr Laeger. 2013;175:1706-7

Siwach SB, Gupta A. The profile of acute poisonings in Harayana Rohtak Study. J Assoc Physicians India. 1995;43:756-9

Mehrpour O, Singh S. Rice tablet poisoning: a major concern in Iranian population. Hum Exp Toxicol. 2010;29:701-2 DOI: https://doi.org/10.1177/0960327109359643

Chugh SN, Arora V, Sharma A, Chugh K. Free radical scavengers & lipid peroxidation in acute aluminium phosphide poisoning. Indian J Med Res. 1996;104:190-3

Solgi R, Abdollahi M. Proposing an antidote for poisonous phosphine in view of mitochondrial electrochemistry facts. J Med Hypotheses Ideas. 2012;6:32-4 DOI: https://doi.org/10.1016/j.jmhi.2012.03.011

Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J. 2006;23:1. https://doi.org/10.1136/emj.2004.015941 DOI: https://doi.org/10.1136/emj.2004.015941

Orkun Tolunay, Tamer Çelik, Gülperi Yücel, Ulaş Özdemir, Anıl Atmış, Asena Sucu, Ümit Çelik. Nadir ama Ölümcül Olabilen Bir Zehirlenme: Alüminyum Fosfit Zehirlenmesi. J Pediatr Emerg Intensive Care Med 2017;4:27-9

Gurjar M, Baronia AK, Azim A, Sharma K. Managing aluminum phosphide poisonings. J Emerg Trauma Shock. 2011;4:378-84 DOI: https://doi.org/10.4103/0974-2700.83868

Mehrpour O, Jafarzadeh M, Abdollahi M. A systematic review of aluminium phosphide poisoning. Arh Hig Rada Toksikol. 2012;63:61-73 DOI: https://doi.org/10.2478/10004-1254-63-2012-2182

Etemadi-Aleagha A, Akhgari M, Iravani FS. Aluminum Phosphide Poisoning-Related Deaths in Tehran, Iran, 2006 to 2013. Medicine (Baltimore). 2015;94:1637 DOI: https://doi.org/10.1097/MD.0000000000001637

Chaudry D, Rai AS. N-acetyl cysteine in aluminum phosphide poisoning: Myth or hope. Indian J Crit Care Med. 2014;18:646-7 DOI: https://doi.org/10.4103/0972-5229.142172

Chacko J, Shivaprasad C. Fatal aluminium phosphide poisoning due to myocardial depression refractory to high dose inotropic support and intra-aortic balloon counterpulsation. Indian J Crit Care Med. 2008;12:37-8 DOI: https://doi.org/10.4103/0972-5229.40949

Shadnia S, Mehrpour O, Abdollahi M. Unintentional poisoning by phosphine released from aluminum phosphide. Human Exper Toxicol 2008;27:87–89 DOI: https://doi.org/10.1177/0960327107086241

Musshoff F, Preuss J, Lignitz E, Madea B. A gas chromatographic analysis of phosphine in biological material in a case of suicide. Forensic Sci Int. 2008;177:35–38 DOI: https://doi.org/10.1016/j.forsciint.2007.12.007

Shields LBE, Hunsaker DM, Hunsaker Iii JC, Ward MK. Toxicologic findings in suicide: a 10-year retrospective review of Kentucky medical examiner cases. Am J Forensic Med Pathol. 2006;27:106–112 DOI: https://doi.org/10.1097/01.paf.0000220913.19508.99

Soltaninejad K, Nelson LS, Bahreini SA, Shadnia S. Fatal aluminum phosphide poisoning in Tehran—Iran from 2007 to 2010. Indian J Med Sci. 2012;66:66–70 DOI: https://doi.org/10.4103/0019-5359.110909

Dias D, Mendonc¸a MC, Real FC, Vieira DN, Teixeira HM. Suicides in the Centre of Portugal: seven years analysis. Forensic Sci Int. 2014;234:22–28 DOI: https://doi.org/10.1016/j.forsciint.2013.10.034

Siwach SB, Gupta A. The profile of acute poisonings in Harayana Rohtak Study. J Assoc Physicians India. 1995;43:756-9

Hajouji-Idrissi M, Oualili L, Abidi K, et al. Severity factors of aluminium phosphide poisoning (Phostoxin). Ann Fr Anesth Reanim. 2006;25:382–385 DOI: https://doi.org/10.1016/j.annfar.2005.12.004

Murali R, Bhalla A, Singh D, et al. Acute pesticide poisoning: 15 years experience of a large North-West Indian hospital. Clin Toxicol (Phila). 2009;47:35–38 DOI: https://doi.org/10.1080/15563650701885807

Ekinci F, Yıldızdaş RD, Horoz ÖÖ, Tolu Kendir Ö 3, Petmezci E, Tolunay İ, Yılmaz HL. Aluminium Phosphide Poisoning: Two Pediatric Patients and Two Different Clinical Outcomes. J Pediatr Emerg Intensive Care Med 2017;4:72-76 DOI: https://doi.org/10.4274/cayd.41275

Tolunay O, Çelik T, Yücel G, Özdemir U, Atmış A, Sucu A, Çelik Ü. A Rare but Potentially Fatal Poisoning; Aluminum Phosphide Poisoning. J Pediatr Emerg Intensive Care Med 2017;4:27-29 DOI: https://doi.org/10.4274/cayd.29484

Hakimoğlu S, Dikey İ, Sarı A, Kekeç L, Tuzcu K, Karcıoğlu M. Successful Management of Aluminium Phosphide Poisoning Resulting in Cardiac Arrest. Turk J Anaesth Reanim 2015; 43: 288-90 DOI: https://doi.org/10.5152/TJAR.2015.75010

Demir U, Hekimoğlu Y, Aşırdizer M, Etli Y, Kartal E, Gümüş O. A case who died due to the suicidal intake of aluminum phosphide. Cumhuriyet Medical Journal 2017;39:458-465 DOI: https://doi.org/10.7197/cmj.v39i1.5000206760

Downloads

Published

2018-03-16

Issue

Section

Case Report

How to Cite

1.
Karadeniz H, Boz H, Ketenci H Çetin. Aluminium Phosphide Poisoning which Occuring with an Unusual Accident and Resulting in Death: Case Report. Bull Leg Med [Internet]. 2018 Mar. 16 [cited 2025 Sep. 6];23(2):129-32. Available from: https://www.adlitipbulteni.com/index.php/atb/article/view/1187